Uppsala
Ages 18–60
Healthy individualsStudy 1137
We are looking for healthy individuals to participate in a clinical trial of an investigational drug designed to prevent and treat lung diseases.
The purpose of the study is to evaluate the effect of two other medications (orlistat and itraconazole) on the levels of the study drug, buloxibutide, in the body.
Target group: healthy men and women, ages 18–60
Criteria for participation:
- Be healthy
- BMI between 18.5–30 kg/m2
- Do not have hard-to-access veins or a fear of needles
- Must not regularly use nicotine or tobacco products
- Do not take any medications or dietary supplements
- Do not have high blood pressure
- Must not have participated in another drug study in the last three months
- Must not have donated blood in the last three months (or plasma in the last month)
- Be willing to use a dual barrier method during heterosexual intercourse (i.e., condoms or male sterilization) AND use approved contraceptives, be sterilized, or be postmenopausal, and not be pregnant, intend to become pregnant, or be breastfeeding during the course of the study (women)
The study consists of three visits to our clinic in Uppsala: a health check-up, a dosing visit, and a follow-up visit. During the dosing visit, you will stay overnight at the clinic for 14 days. The dosing visit is divided into three periods, during which you will receive doses of the study drug twice a day.
During the second phase, depending on which group you are randomly assigned to, you will receive the study drug in combination with either orlistat or itraconazole.
Compensation:
46,504 SEK in compensation for your participation.
Schedule
| GROUP | Health check-up (visit 1) | Inpatient stay at the clinic (visit 2) | Visit 3 |
| 1 | May 12, Group 1 May 13, Group 2 May 25, Group 3 June 10, Group 4 | May 19 – June 2 | June 9 |
| 2 | May 26 – June 9 | June 16 | |
| 3 | June 2 – June 16 | June 24 | |
| 4 | June 23 – July 7 | July 15 |
More information and registration
Would you like to participate in the study? Submit an expression of interest using the form below.
Do you have questions or want to know more? Call 018-30 33 99 or email info@ctc-ab.se.
The study has been approved by the Ethical Review Authority. Your participation is voluntary, and you can withdraw at any time. The information you provide will be processed in accordance with the General Data Protection Regulation (GDPR).
